Given the scattered and erythematous 1 to 2mm macules and patches in a flagellate pattern on the shoulders, back, and neck, the differential diagnosis included shiitake mushroom dermatitis, bleomycininduced flagellate dermatitis, dermatomyositis flagellate erythema, excoriation disorder, dermatographism, and keratosis lichenoides chronica. This is a rare condition, regarded by some as a variant of lichen planus. Generalized keratosis lichenoides chronica induced by. Keratosis lichenoides chronica is a rare dermatosis characterized by a distinctive seborrheic dermatitislike facial eruption, together with violaceous, papular. It is a progressive disease characterized by the linear and reticulate appearance of erythematoustoviolaceous keratotic and lichenoid papules over the trunk and limbs and a seborrheiclike dermatitis over the face 2,3. Keratosis lichenoides chronica with tiny keratotic papules that tend to be arranged in a striaelike pattern in the antecubital fold.
Pityriasis lichenoides chronica presenting with bilateral. Keratosis lichenoides chronica represents a distinct entity, a rare disease of unknown etiology and pathogenesis, with clinical manifestations. Treating lichenoid keratosis will usually begin with using a prescription medicated topical cream that contains corticosteroids as the main ingredient or covered with liquid nitrogen. The histological examination of klc reveals lichenoid dermatitis with hyper and parakeratosis. Keratosis lichenoides chronica jama dermatology jama network. Histopathological characteristics concordant with keratosis lichenoides chronica were finally evidenced after several nonspecific biopsies. This cutaneous eruption appears to be previously unreported, and we propose the term keratosis lichenoides chronica. Papers published on keratosis lichenoides chronica or synonyms from 1886 to 2014 to the best of our knowledge, in the last 128 years 1986 2014, 120 papers were published with keratosis lichenoides chronica or its synonyms as a. Two cases of pediatric keratosis lichenoides chronica with. Media in category keratosis lichenoides chronica the following 3 files are in this category, out of 3 total. To date there have been no reports of lichenoid keratosis turning into malignant skin tumours. Keratosis lichenoides chronica or nekams disease is a rare mucocutaneous dermatosis characterized by keratinization. Tehran, iran, and monroe, ml we are reporting a case of keratosis iichenoides chronica.
A young boy developed childhood keratosis lichenoides chronica. Keratosis lichenoides chronica klc is a rare chronic progressive dermatosis of unknown aetiology characterized by lichenoid hyperkeratotic papules typically arranged in a linear or reticulate pattern on the extremities or on the trunk, warty erythematosquamous plaques and seborrhealike dermatitis on the face. Department of dermatology, saintphilibert hospital, catholic university of. A case of pediatric keratosis lichenoides chronica with. The etiology of klc is unknown, but it may be associated with internal. This is a chronic dermatosis characterized by seborrheic dermatitislike facial eruption and purplish papulonodular lesions of the extremities. The diagnosis was keratosis lichenoides chronica klc, a mucocutaneous skin disease of unknown cause.
To the editor keratosis lichenoides chronica klc is a rare dermatosis characterized by lichenoid keratotic papular lesions arranged in a linear or reticular pattern on the extremities andor trunk and a distinctive seborrhoeic dermatitis or rosacea. Marked response to puva in combination with acitretin. Keratosis lichenoides chronica klc is a rare mucocutaneous eruption, with just greater than 70 cases reported in the literature. Jan 01, 2001 to the editor keratosis lichenoides chronica klc is a rare dermatosis characterized by lichenoid keratotic papular lesions arranged in a linear or reticular pattern on the extremities andor trunk and a distinctive seborrhoeic dermatitis or rosacea. Keratosis lichenoides chronica occurs in childhood and may be seen soon after birth. Keratosis lichenoides chronica a case report and literature. Keratosis lichenoides chronica klc, also known as nekams disease, is a rare and chronic disorder of keratinization of unknown etiology 1,2. Keratosis lichenoides chronica italian ministry of health. Pdf case of keratosis lichenoides chronica with atypical. This symmetrical rash was composed of thick hyperkeratotic plaques, some with a linear distribution, and accentuated over tattooed skin. The course of the disease is chronic, progressive, and it is resistant to various treatment options, so despite.
Keratosis lichenoides chronica treatment develop some form of fat or oil and grime oils along with other skin product as when androgen and could be utilize mild towards your skin feel good. Keratosis lichenoides chronica klc is a rare chronic progressive dermatosis of unknown aetiology characterized by lichenoid hyperkeratotic papules typically arranged in a linear or reticulate. Histologically, the eruption shows parakeratosis, orthohyperkeratosis, atrophy of the malpighian layer, and a lichenoid histiocytic and lymphocytic dermal infiltrate. The problem in this longlasting disease is generally the treatment, not the diagnosis. The study of keratosis lichenoides chronica has been mentioned in research publications which can be found using our bioinformatics tool below. The clinical picture, histopathology and the criteria for the diagnosis of this rare dermatosis are discussed.
Keratosis lichenoides chronica klc is a rare condition characterised by the asymptomatic development, over several years, of scaly papules on the limbs and trunk, sometimes distributed in a linear or reticulate netlike pattern. Keratosis lichenoides chronica with tiny keratotic papules that tend to be. Introduction keratosis lichenoides chronica klc, also known as nekams disease, is a rare dermatological disorder of keratinization characterized by development of violaceous, hyperkeratotic papules and nodules typically arranged in a linear or reticulate pattern, mostly. Lichenoid keratosis pictures, symptoms, causes, treatment. Here, we present adultonset klc, which was treated by narrowband ultraviolet b nbuvb monotherapy. Keratosis lichenoides chronica is a chronic dermatosis, generally of benign nature, yet refractory to treatment. Pdf keratosis lichenoides chronica represents a distinct entity, a rare disease of unknown etiology and. Pityriasis lichenoides is an erythematous, papulosquamous, tcellmediated dermatosis. Jan 22, 2016 this symmetrical rash was composed of thick hyperkeratotic plaques, some with a linear distribution, and accentuated over tattooed skin. Keratosis lichenoides chronica, journal of the european. A mild case of adultonset keratosis lichenoides chronica. Keratosis lichenoides chronica klc is an acquired keratinization disorder that is rare in childhood.
It is not known what causes the reaction, but triggers include minor trauma such as friction, drugs, dermatitis, and sun exposure. Keratosis lichenoides chronica klc is a rare acquired disease of adulthood, of unknown etiology, characterized by keratotic parallel linear lesions, retiform plaques, and keratotic, often. Keratosis lichenoides chronica is characterized by violaceous, papular, and nodular lesions in a linear and reticulate pattern on the extremities and a seborrheic dermatitislike facial eruption. Keratosis lichenoides chronica is a rare chronic dermatosis that typically presents in adolescents or young adults as a widespread symmetrical lichenoid eruption, formed by hyperkeratotic papules that adopt a reticulate, striated, or linear pattern. Although some authors have considered klc to be a variant of lichen planus, klc is generally considered a distinct. Response of keratosis lichenoides chronica to efalizumab therapy. Lichenoid keratosis is an inflammatory reaction arising in a regressing existing solar lentigo or seborrhoeic keratosis. Keratosis lichenoides chronica is a rare dermatosis characterized by a distinctive seborrheic dermatitislike facial eruption, together with violaceous, papular, and nodular lesions on the extremities and trunk typically arranged in a linear and reticulate pattern. Lichenoid keratosis can be removed if desired by liquid nitrogen, electrosurgery or curettage. Keratosis lichenoides chronica jama dermatology jama. A clinical and histolopathological study of pityriasis lichenoides. Keratosis lichenoides chronica klc, also known as nekams disease, is a rare and chronic disorder of keratinization of unknown. Keratosis lichenoides chronica klc is a rare keratotic disorder of unknown origin.
Pityriasis lichenoides chronica typically does not ulcerate or scar. Keratosis lichenoides chronica journal of the american academy. Histologically, keratosis lichenoides chronica is characterised by a lichenoid reaction pattern with marked basal cell death and vacuolar degeneration. Seventh honey is use like a facial skin layer variety will help you create more damaged skin care program. Keratosis lichenoides chronica primary care dermatology. Pdf keratosis lichenoides chronica in a child antonio.
Pityriasis lichenoides chronica plc is a skin disease that causes the development of small, scaling, raised spots papules on the skin. Multiple eruptive lichenoid keratoses may be effectively treated with the oral retinoid, acitretin. Pityriasis lichenoides et varioliformis acuta photo of the pityriasis lichenoides et varioliformis acuta or mucha habermanns disease, showing the right leg specialty. Keratosis lichenoides chronica also known as nekams disease is a rare dermatosis characterized.
Keratosis lichenoides chronica klc is a rare chronic disease characterized by violaceous, papular and nodular lesions typically arranged in a linear and reticulate pattern. Pityriasis lichenoides british association of dermatologists. Department of dermatology, saintphilibert hospital, catholic university of lille, lomme 2. It is chronic and progressive usually affecting individuals aged 2040 years.
Keratosis lichenoides chronica in a child, pediatric. Keratosis lichenoides chronica klc is a rare disease, with approximately 70 cases reported in the literature. Keratosis lichenoides chronica klc is a rare chronic progressive dermatosis of unknown aetiology characterized by lichenoid hyperkeratotic papules typically arranged in a linear or reticulate pattern on the extremities or on the trunk, warty erythematosquamous plaques and seborrhealike dermatitis on. Keratosis lichenoides chronica is a rare skin condition that i occasionally encounter in my the woodlands dermatology and conroe dermatology offices. Pityriasis lichenoides is an uncommon, acquired, idiopathic, selflimiting skin disease that poses a challenge to patients and clinicians to diagnose and treat. It is characterized by polygonal, flattopped, violaceous papules and plaques with overlying, reticulated, fine white scale wickhams striae, commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa. As it is still unclear whether the dermatosis is an independent disease.
Our 54yearold man patient, who is the 40th case reported in the literature, presented with a 15 year history of skin lesions, which were clinically, histopathologically, immunohistologically and. Pityriasis lichenoides chronica plc is considered as mild and or plc were enrolled into the study. Disease bioinformatics research of keratosis lichenoides chronica has been linked to keratosis, lichenoid eruptions, lichen planus, lichen disease, exanthema. Pruritic and erythematous rash resembling marks caused by.
Keratosis lichenoides chronica is a rare chronic dermatosis that typically. Response of keratosis lichenoides chronica to efalizumab. When a person opts to use liquid nitrogen to remove the lichenoid keratosis it is called liquid nitrogen and curettage. Keratosis lichenoides chronica klc is a rare and chronic skin disease characterized by erythema, keratotic and lichenoid papules are distributed symmetrically. Pityriasis lichenoides an overview sciencedirect topics. Keratosis lichenoides chronica klc is characterised by violaceous, papular and nodular lesions in a linear or reticulate pattern. Material must be accompanied by the required transfer statement see authorship form. Read keratosis lichenoides chronica in a child, pediatric dermatology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. These authentic cases of keratosis lichenoides chronica klc showed strong clinical and histological similarity, a uniformity indicating that klc is an entity and is distinct from lichen planus.
A 20yearold african man presented with clinical and histopathological features of keratosis lichenoides chronica. Keratosis lichenoides chronica represents a distinct entity, a rare disease of unknown etiology and pathogenesis, with clinical manifestations which, although typical, require extensive differential diagnosis. Pdf keratosis lichenoides chronica a case report and. This pdf is available for free download from a site hosted. Keratosis lichenoides chronica and eruptive keratoacanthoma. Both acute and chronic forms are described and represent the. Keratosis lichenoides chronica pathology dermnet nz.
1270 772 945 657 1228 640 479 599 992 1533 130 630 538 988 811 168 972 1359 197 1052 1209 583 1219 1455 1297 1517 168 998 772 1444 641 817 697 973 702 1398 1483 722 480 118